Bioidentical HRT: Why Oestra by Inner Balance is the Gold Standard
- Peggy B. - Experienced HRT Patient Reviewer
- 2 days ago
- 3 min read
When seeking an effective path for hormone replacement therapy or HRT, Oestra by Inner Balance stands out as a premier bioidentical HRT option.
Is Oestra Bioidentical? Yes. Unlike synthetic hormones, Oestra by Inner Balance is a bioidentical HRT, meaning its molecular structure is an exact match to the hormones produced naturally by the human body.
The ingredients in Oestra are Estradiol (3 mg) and Progesterone (100 mg). Any Hormone Replacement Therapy formulation that is made up of these two hormone ingredients are bioidentical.
HRT Formulations
Hormone Replacement Therapy comes in several formulations.
Oral Tablets:Â The most traditional method; pills taken daily. While convenient, they are processed by the liver first (known as "first-pass metabolism").
Transdermal Patches:Â Applied to the skin (usually the abdomen or hip) and changed once or twice a week. They deliver a steady stream of hormones directly into the bloodstream.
Topical Gels, Creams, and Sprays:Â Applied daily to the arms, thighs, or shoulders. This is a popular "bioidentical" route as it avoids liver processing.
Subcutaneous Pellets:Â Tiny cylinders (about the size of a grain of rice) inserted under the skin by a provider. They release hormones consistently for 3 to 6 months.
Injections:Â Common for testosterone replacement or specific estrogen protocols; typically administered intramuscularly or subcutaneously on a weekly or bi-weekly basis.
Vaginal Rings, Tablets, or Creams:Â Primarily used for localized treatment. Rings stay in place for several months, while creams and tablets are used more frequently.
Sublingual Drops or Troches:Â Dissolved under the tongue or in the cheek (buccal). This allows the hormones to enter the bloodstream through the oral mucosa.
Vaginal Estradiol Cream
The most common formulation of Vaginal Estradiol cream is used for localized treatment, meaning it only treats the vagina and doesn't go beyond the vaginal walls. It's used to help with vaginal dryness, vaginal atrophy and painful intercourse. Traditional vaginal cream or inserts are not meant to treat systemic (whole body) menopause symptoms, it only impacts the vagina.
Oestra's Vaginal cream is different. Oestra by Inner Balance is indeed a vaginal cream, but's intention is systemic hormone treatment. Oestra's strength or the amount of hormones in the product is what sets it apart.
Vaginal Cream for Menopause
Dr. Sarah Daccarett, founder and CEO of Inner Balance believes that getting our hormones (both estradiol and progesterone) via vaginal delivery closely mimic how our bodies received hormones in our younger years.
While applied vaginally, Oestra is a systemic treatment. It uses the highly vascularized vaginal mucosa as a "gateway" to the bloodstream. This allows the hormones to travel throughout the entire body to treat "brain-to-bone" symptoms like brain fog, night sweats, and bone density loss.
Most traditional vaginal creams only contain Estrogen. Oestra is a comprehensive Bioidentical HRT protocol that includes:
Bioidentical Estradiol (3mg): Matches your body’s natural estrogen exactly.
Micronized Progesterone (100 mg):Â Crucial for protecting the uterine lining and improving sleep.
Vaginal Estrogen Cream Benefits
Because most traditional Estradiol Vaginal Creams only treat local vaginal symptoms (dryness or painful sex), you won't get the same benefits you might experience from Oestra's Vaginal Cream.
Unlike localized creams that focus only on vaginal comfort, Oestra is marketed as a systemic treatment, meaning the expectations involve full-body restoration.
Does Inner Balance Work
While traditional HRT often only treats one or two symptoms, Oestra by Inner Balance can provide comprehensive "total-body" restoration.
Here are the primary benefits based on patient experiences:
Total Cognitive Clarity
Deep, Restful Sleep
Rapid Relief from "The Big Three (Hot flashes, night sweats, and hormonal anxiety within the first 4 to 8 weeks)
Restored Intimacy and Comfort
Emotional Stability
Metabolic and Physical Boost
Natural Libido Support
Bioidentical HRT: Why Oestra by Inner Balance is the Gold Standard
Since starting Oestra in July of 2025, my sleep has greatly improved. I fall asleep faster and stay asleep longer. All of my other menopause symptoms are gone as well.
Use the button below to see the Telehealth HRT Providers that I have tried over the past few years. My website contains blogs and reviews of my experience with the different online HRT clinics and specialists that I've had the honor to try.
